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???????????? (2,4????????????) ????????? ?? ??????? ????? ???????? ????????????? ????????, ??????????? ??? ????, ????? ??????? ????????? ??????????? ????.

2,4???????????? ??? ?????? ??????? ?????????? ??? ???????? ?????? ? ????????? ? ???????? ????? ???????????. ? ?????????, ??? ???????? ?? ?????? ???????, ? ??????? ??????????? ??????? ???????????, ????? ?????????? ? ?????????? ??????. ? ???? ??, ??????? ??????, ??? ?? ???????? ???????? ????????? ????.

????????????? (?????????? ???????, 2, 4, 6?????????????) ??????????? ??? ?????????? ??? ??????? ?????? ? ???????????? ???. ??? ????????????? ???????? ?? ????? ???????????? ??????????? ? ????? ???????????? ???????? ??????, ??? ??????? ????? ????????? ?????????? ??????? ??????????. ??????????? ?????? ? ???? 1% ????????; ??? ??????? ????????? ????? ?????? ??????????? ?????? 5% ???????.

?????????? ???????, ??????? ????????????????????, ?????????. ??? ?????????? ?????? ? ???? ? ?????? ????, ?? ? ???????? ?????? ?? ???????????.

????????? ??????????? ?????????? ????????????? ?????, 2, 4, 6????????????? ???????? ????? ??????? ????????. ?? ???????? ???????????? ???????? ??????, ?? ???????? ??????????, ?? ??????????? ?????????? ??????????. ????????? ??????????? ???????????? ????????? ? ????. 43.

?????? ??????? (???????????????? ???????) ????????? ? ???? ??????????????? ???????? ??????? ? ??????????? ????????? ?????????? ???????. ??????????? ??? ??????? ?????????, ?????????, ?????????? Trichomonas vaginalis, ? ?. ?. ??????????? ? ???? ??????? 1% ??????? ?? ?????????? ??????? ??? ? ???? ?????????????.

??? ????????? ????????????? ?????? ?????????? ??????? ?? ???? ?????????? 1?????2,4,6??????????????, ???????? ???????? ?????????? ?????????? ????????? ?????????? ????????? ????? ??????. ????? ??? ?? ????????? ?????????? ?? ??????????? ???? ?????????? ?? ??????????, ????????? ??? ????? (?? ??????).

????? ?????????? ?????????? ?????? Carlisle, Manufacture, Handling and Use of Hydrocyanic Acid, lnd. Eng. Chem., 25, 959 (1933).

Cutting, Mehrens, Tainter, Actions and Uses of Dinitrophenol, J. Am. Med.

Assoc., 101, 193 (1933). Olsen, Goldstein, The Preparation of Picric Acid from Phenol, lnd. Eng. Chem., 16, 66 (1924).

Tainter, Stockton, Cutting, Dinitrophenol in the Treatment of Obesity, J. Am. Med. Assoc., 105, 332 (1935).

???????????? ??????????

Machle, Scott, Treon, J. lnd. Hyg. Toxicol., 22, 315 (1940); 24, 5 (1942): C. A. 35, 805 (1941); 36, 2021 (1942).




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